Yury Berezhko was born in Komsomolsk-on-Amur and began to play under the guidance of his father. He continued his Volleyball education in Yaroslavl, where he moved at 16. In summer of 2004 Berezhko signed a contract with "Dynamo" (Moscow).
Not always being in the starting line-up of the Moscow team, Yury Berezhko nevertheless managed to attract attention of the Russian national team head coach Zoran Gajic, who included the young player to the application for the 2005 Euroleague. Yury's debut in the national team took place on June 25, 2005 for the match against Finland (3:1).
The next appearance in the team of Russia happened within a year, and was largely accidental: he had to replace the injured Sergey Tetyukhin at the World championships. Berezhko however failed to show his talent in Japan.
But Yuri jumped brilliantly on the new opportunity to gain a foothold in the starting line-up of the national team. By the decisive matches of the World League 2007 Vladimir Alekno's team lost from trauma experienced Pavel Abramov and was thereby with only two receiving players - Berezhko and Alexander Korneev. Young players never before played in such critical matches but bravely withstood reception, and Yuri was also named the best spiker of the tournament. In autumn 2007 Berezhko brilliantly played at the European Championships, where he again gained the prize of the best spiker (60% efficiency in the attack), and at the World Cup he was already a full-fledged player in the starting composition. Before the start of the championship of Russia, Yury Berezhko was elected captain of the "Dynamo" (Moscow).
In addition to gambling, variational and effective game in attack and reliable reception, Yury Berezhko has also a powerful serve. In 2009 Yury Berezhko was awarded as best server of the European Championships, where the Russian team finished fourth. In eight games he made 12 aces (on average per game - 0.44 aces).
In May 2010, Yuri Berezhko signed a contract with the Italian club of "Modena" for two years.